How to print pharmaceutical packaging labels with

2022-09-30
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How to use the traditional letterpress process to print the pharmaceutical packaging label

the pharmaceutical label is an indispensable product identification of drugs. It can be said that it is also the ID card of pharmaceutical products and an important production process in the packaging and printing process. The main contents of pharmaceutical labels should usually include: product name, adaptive symptoms, production date, production batch number, specification, quantity, precautions, shelf life, dosage and usage, storage environment requirements, manufacturer name, etc. Product labels are printed in monochrome, or overprinted or overprinted in multicolor; Some are printed with offset paper, others are printed with coated paper and other self-adhesive paper. From the perspective of health and safety, the printing quality control of medical labels is a very important technical link. Therefore, the instructions in the product layout must be clear and clear, and the printed color must be accurate and consistent. It can be seen that medical labels should have the requirements of easy identification and good anti-counterfeiting effect. A considerable part of medical labels are printed by traditional letterpress printing technology. The author has also printed medical label products in clinical production practice in the past, and has personal experience of letterpress printing technology of medical product labels. This article talks about the experience of process technology control on the practice of letterpress printing process

reasonable design of printing color of medical label page

medical labels generally adopt neutral series colors, among which the printing page with cooler colors can give patients a sense of peace and restlessness. The design of light red and golden red in order to develop this kind of material, the golden printing page can make patients have the psychological feeling of restoring vitality, Yang Qi, health and vitality. The blue and silver layout can give patients a sense of security. The color design of the printing page can also be matched according to the differences in the use characteristics of drugs. For tonic and nutritional drugs, the printing layout is mainly designed in gold, bronze, coffee or red, with other colors as appropriate. Drugs for analgesia, sedation, sleeping, blood pressure reduction and cardiovascular diseases should be mainly in green, blue and other colors. The insect repellent is mainly packed in white with other light colors. The labels of anti-inflammatory cold drugs, such as cough relieving and expectorant, Qingliang Jiedu granules, are generally printed in green. The reasonable design of printing color of medical labels can make patients feel safe in psychology and obtain better curative effect

use the change principle of three primary colors to make accurate ink allocation

the purity of the printing color of medical labels is the basic requirement of product quality. Therefore, how to make accurate ink allocation is a very important technical link. According to the change principle of the three primary colors, except for gold and silver colors (the substrate is the material of aluminum spray paper), any color can be mixed and blended with different proportions of the three primary colors. For example, the three primary color inks can become approximately black after equal mixing and blending. Three primary color inks are mixed in equal amounts and different proportions of white ink are added to form light gray inks with different tones. If the three primary color inks are mixed according to various proportions, they can be mixed into a variety of intermediate colors or multicolor with different hues, but their hues prefer the primary color hue with a large proportion. If the two primary color inks are mixed equally, they can be adjusted to become standard intermediate colors; After mixing the two primary color inks in different proportions, they can be matched into a variety of intermediate colors with different hues, but their hues tend to be primary colors with large proportions. In addition, any color of ink, after adding white ink, its hue will appear brighter. On the contrary, after adding black ink, its hue becomes dark. Whether the method of blending ink is appropriate directly affects the color quality of printing. Therefore, when mixing ink, we should first analyze the excellent phase according to the original to determine which kinds of ink should be used to mix properly. For example, if you want to adjust lake blue ink, it can be preliminarily determined by visual inspection and practical experience. Among them, white ink is the main color, malachite blue is the auxiliary color, which should be slightly added. If you want to be darker, you can slightly add magenta blue. As long as the main color is determined, other colors are auxiliary colors, which should be added gradually and stirred evenly. Then, two pieces of paper (the same as the printing paper) are used, one of which is coated with a little adjusted ink, and the other piece of paper is used to scrape it until it is roughly close to the thickness of the printed ink layer, and then compared with the original to see whether it is appropriate. When comparing the sample, you should compare the relatively thin and light parts of the ink layer of the scraping sample on the paper to see more accurately. When adjusting ink, we should also master a principle, that is, try to use less ink of different colors, that is, if we can use two kinds of ink, we should not use three kinds of ink to adjust, so that it can achieve efficient measurement, so as not to reduce the gloss of the ink. On the other hand, the ink color of scraping sample should be slightly darker than the primary color, so that the printed color sample can be accurate or close

after the ink color of the small samples is adjusted, they can be adjusted in batches according to their respective ink proportion

some technological measures to improve the printing quality of label products

1. Pay attention to the technical control of paper cutting process. The accuracy of paper specifications directly affects the overprint accuracy of products. Because of different machine structures, their front gauge and pull gauge positions are not the same. In this way, if the edge of the paper is not cut squarely enough, and there are beveled edges or wavy edges, it will cause inaccurate overprint. This requires that the edges of the paper must be cut into right angles and straight lines for the products with glue convex combination, and there must be no beveled edges or wavy edges. In order to improve the cutting accuracy of paper, the thickness of cutting must be strictly controlled, because the thicker the paper stack is, the softer the paper is, the more severe the paper surface deformation is when the paper presser is pressed down. Therefore, the less the thickness of each stack is, the more conducive it is to improve the cutting accuracy of paper. In addition, the blade edge should also be kept sharp, and the appropriate blade angle should be selected according to the hardness of the paper, which is also an important measure to improve the cutting accuracy

2. Pay attention to the reasonable selection of the bottom support of the printing plate. The characteristics of the plate base material of the relief printing machine with circular flattening structure have a great impact on the printing pressure, overprint accuracy and ink quality. The traditional wooden bottom support is not solid, with poor squareness, flatness and stability. It is prone to bow and deformation, and the printing quality is difficult to guarantee. Therefore, relief printing should use solid, flat, square, stable aluminum or cast iron and other metallic materials, which is a reliable guarantee to improve the accuracy of overprint and ink quality

3. Pay attention to the rational use of paper. Paper is very sensitive to the changes of temperature and humidity in the external environment, especially the paper just produced, which is most prone to expansion and variation due to the changes of temperature and humidity, resulting in inaccurate overprint of products. In order to reduce the chance of this bad situation, the newly produced paper usually needs to be stored for about half a year after being transported back by the printing factory, so that the paper can be put into use after its characteristics are relatively stable, so it is not easy to have overprint problems. In addition, it is also conducive to the registration of products by hanging the paper and placing the cut paper in the printing workshop for several days to balance with the temperature and humidity of the printing workshop for a period of time

4. Pay attention to the selection of appropriate printing plates. Letterpress printing process adopts copper plate, zinc plate, resin plate and other plates. Due to the different characteristics of printing plate materials, there are also obvious differences in their printing suitability and printing quality. According to the inkiness, ink transmission, gloss and pressure effect, resin plate performs best, copper plate takes second place, and zinc plate performs worst. In terms of dot printing quality, the dot printing quality of copper plate is better, and the dot expansion rate is the least. Therefore, according to the characteristics of products, we should reasonably select plates for printing, so as to better improve the printing quality of products

5. Pay attention to the reasonable arrangement of printing color sequence. The protective devices should be firm and reliable. Arranging the printing color sequence is an important measure to improve the printing quality. The reasonable arrangement of the printing color sequence should be mainly considered from these aspects, that is, considering the arrangement of the printing color sequence according to the characteristics of the substrate; Consider arranging the color sequence according to the differences in the structure of the printing machine; Arrange the color sequence according to the different graphic structure of the printing layout; Consider arranging the color sequence according to the color characteristics of the original; Arrange the color sequence according to the difference of ink characteristics; Arrange the color sequence according to the drying characteristics of the ink. This scientific and reasonable arrangement of printing color sequence can better improve production efficiency and product printing quality

6. Pay attention to the lining technology. Lining is the medium to realize pressure and imprint transfer. Its characteristics also affect the registration and ink quality of products. Therefore, the deformation coefficient of the lining material should be smaller, and the material should be neutral and hard. At the same time, the thickness of the lining must be determined in strict accordance with the technical parameters of the equipment specifications. In addition, the lining must be tightly wrapped and tight, and there must be no virtual looseness or bulging. Do not repeatedly patch or excavate on the lining to prevent inaccurate overprint and ghosting

7. Pay attention to adjust the appropriate printing pressure. The printing pressure should be adjusted evenly and moderately. Too much pressure is easy to stretch and deform the printing sheet, resulting in inaccurate overprint

therefore, the appropriate printing pressure should be adjusted. The printing pressure should not be biased, so as not to make the edge of the printing page rough and enlarged

8. Pay attention to the overprint production cycle of the product. After printing the previous color or several colors of the printed matter, those that can be overprinted should be overprinted immediately, so as to avoid stretching and variation of the printed matter due to too long delay, resulting in inaccurate overprinting and quality failure

9. Pay attention to prevent the printing products from being sticky and dirty. When printing pharmaceutical label products with relief process, it is easy to cause the back of the product to rub dirty when encountering the conditions of good gloss of the paper, acidic paper, affecting the drying of the ink layer, large printing ink supply, slow drying speed of the ink, and excessive stacking of semi-finished products. The solution is to adopt the "deep ink thin printing" process for printing, that is, to darken the ink hue and make the printing ink layer thinner. In this way, it can not only meet the requirements of printing ink color, but also reduce the chance of dirt. In addition, you can add some dry oil in the ink to dry the ink layer in time; Add some anti sticking agent in the ink, so that the ink layer on the surface of the print is not easy to transfer; Spray powder on the surface of the printing ink layer appropriately to prevent the surface ink layer from transferring to the back of the printing; The stacking volume of printing semi-finished products shall be appropriately reduced, and the semi-finished products shall be hung in small stacks with drying racks

10. Pay attention to prevent the printing plate from being pasted. When the printing pressure is uneven or too heavy, the ink particles are too thick, the ink fluidity is poor, the paper surface appears powder dropping, roughening, the height adjustment of the inking roller is inappropriate, and there is a poor contact between the inking roller and the inking roller, it is easy to cause the plate pasting phenomenon. Therefore, corresponding measures should be taken to adjust it

11. Pay attention to prevent the ink color on the printing plate from crystallizing. When too much dry oil is added to the ink, and the ink layer on the surface of the print is excessively dried to form a glass surface, it is difficult for the overprinted ink to adhere to the bottom color of the print. Even if it can be printed, the ink color only shows obvious blooming, which is the phenomenon of ink film crystallization. To prevent the crystallization of printing ink film, we should strictly control the amount of dry oil and try to shorten the overprint production cycle. yes

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